Neurobehavioral Genetics Annual Retreat

Annenberg Community Beach House

415 Pacific Coast Hwy

Santa Monica, CA 90402

February 25, 2016


Register Here” – Registration Deadline February 12, 2016

The Gladstone-UCLA Neurodegenerative Disorders Symposium

Nov. 19 2013 8:30AM to 5:00PM

Neuroscience Research Building (NRB) Auditorium

635 Charles E. Young Drive South, Los Angeles, CA 90095


8:30am John Mazziotta and Lennart Mucke
Introduction -including brief overviews of UCLA and Gladstone programs and purpose of symposium.

Morning Molecular Networks

9:00am Steve Finkbeiner
Disease-specific cascades converging on common mechanisms of neurodegeneration

9:25am Ming Guo
Mitochondria: A convergence point of multiple neurodegenerative disorders

9:50am Break

10:10am Li Gan
Targeting protein turnover in proteinopathies of the aging CNS

10:35am Jeff Bronstein
Counteracting environmental risk factors in Parkinson’s disease

11:00am Break

11:20am Yadong Huang
Counteracting genetic risk factors in Alzheimer’s disease

11:45am Dan Geschwind
Using genetics and systems biology to unravel the complex pathogenesis of neurodegenerative disorders

12:10pm Lunch Break

Afternoon Cellular Networks

1:10pm Lennart Mucke
Mechanisms and treatment of neural network dysfunction in Alzheimer’s disease and other dementias

1:35pm Istvan Mody
Critical roles of interneurons in health and disease

2:00pm Jorge Palop
Restoring brain rhythms and cognition in Alzheimer models by enhancing inhibitory interneuron function

2:25pm Break

2:45pm Mayank Mehta
Neurophysiological substrates of learning and memory

3:10pm William Seeley
Radiological imaging of network dysfunction in neurodegenerative diseases

3:35pm Break

4:00pm Joint Seminars in Neuroscience Lecture of the Brain Research Institute
Anatol Kreitzer
Basal Ganglia Circuit Dysfunction Underlying Parkinson's Disease and Dyskinesia

5:00pm Reception

The UCLA Integrative Center for Neurogenetics Inaugural Symposium

Feb. 21 2013 8:30AM to 5:00PM

Neuroscience Research Building (NRB) Auditorium

635 Charles E. Young Drive South, Los Angeles, CA 90095


Nelson B. Freimer, M.D. - Opening Remarks

Stephen T. Warren, Ph.D.
Fragile X Syndrome: Molecular Mechanisms and Therapeutic Approaches

Harry T. Orr, Ph.D.
Understanding Genetics of Neurodegeneration: SCA1

Leslie B. Vosshall, Ph.D.
The Neurogenetics of Innate Behavior

Gene E. Robinson, Ph.D.
The Relationship Between Genes and Social Behavior: Lessons from the Honey Bee

Joseph S. Takahashi, Ph.D.
Transcriptional Architecture and Chromatin Dynamics of the Circadian Clock in Mammals

Ying-Hui Fu, Ph.D.
Investigating Human Sleep Behavior Traits

Jonathan Flint, M.D.
Genetic Analysis of Major Depression in 12,000 Chinese Women

Emmanuel Mignot, M.D., Ph.D.
Genetics of Narcolepsy

Daniel H. Geschwind, M.D., Ph.D. - Closing Remarks

* For additional information contact Maribel Estrada at 310-206-2206 or